<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Soares, P.I.P.a</style></author><author><style face="normal" font="default" size="100%">Laia, C.A.T.b</style></author><author><style face="normal" font="default" size="100%">Carvalho, A.a</style></author><author><style face="normal" font="default" size="100%">Pereira, L.C.J.c</style></author><author><style face="normal" font="default" size="100%">Coutinho, J.T.c</style></author><author><style face="normal" font="default" size="100%">Ferreira, I.M.M.a</style></author><author><style face="normal" font="default" size="100%">Novo, C.M.M.d</style></author><author><style face="normal" font="default" size="100%">Borges, J.P.a</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Iron oxide nanoparticles stabilized with a bilayer of oleic acid for magnetic hyperthermia and MRI applications</style></title><secondary-title><style face="normal" font="default" size="100%">Applied Surface Science</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acid concentrations</style></keyword><keyword><style  face="normal" font="default" size="100%">Biocompatibility</style></keyword><keyword><style  face="normal" font="default" size="100%">Biocompatible surfactants</style></keyword><keyword><style  face="normal" font="default" size="100%">Biomedical applications</style></keyword><keyword><style  face="normal" font="default" size="100%">Colloidal Stability</style></keyword><keyword><style  face="normal" font="default" size="100%">High resolution transmission electron microscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrodynamic diameter</style></keyword><keyword><style  face="normal" font="default" size="100%">Iron</style></keyword><keyword><style  face="normal" font="default" size="100%">Iron oxide nanoparticle</style></keyword><keyword><style  face="normal" font="default" size="100%">Iron oxides</style></keyword><keyword><style  face="normal" font="default" size="100%">Magnetic hyperthermia</style></keyword><keyword><style  face="normal" font="default" size="100%">Magnetic resonance imaging</style></keyword><keyword><style  face="normal" font="default" size="100%">Magnetism</style></keyword><keyword><style  face="normal" font="default" size="100%">Medical applications</style></keyword><keyword><style  face="normal" font="default" size="100%">Metal nanoparticles</style></keyword><keyword><style  face="normal" font="default" size="100%">Nanomagnetics</style></keyword><keyword><style  face="normal" font="default" size="100%">Nanoparticles</style></keyword><keyword><style  face="normal" font="default" size="100%">Oleic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Physiological condition</style></keyword><keyword><style  face="normal" font="default" size="100%">Transmission electron microscopy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.scopus.com/inward/record.uri?eid=2-s2.0-84966277057&amp;doi=10.1016%2fj.apsusc.2016.04.181&amp;partnerID=40&amp;md5=22811619aaf3d95dd0e93c091b2db806</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">Elsevier</style></publisher><volume><style face="normal" font="default" size="100%">383</style></volume><pages><style face="normal" font="default" size="100%">240-247</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Iron oxide nanoparticles (Fe3O4, IONPs) are promising candidates for several biomedical applications such as magnetic hyperthermia and as contrast agents for magnetic resonance imaging (MRI). However, their colloidal stability in physiological conditions hinders their application requiring the use of biocompatible surfactant agents. The present investigation focuses on obtaining highly stable IONPs, stabilized by the presence of an oleic acid bilayer. Critical aspects such as oleic acid concentration and pH were optimized to ensure maximum stability. NPs composed of an iron oxide core with an average diameter of 9 nm measured using transmission electron microscopy (TEM) form agglomerates with an hydrodynamic diameter of around 170 nm when dispersed in water in the presence of an oleic acid bilayer, remaining stable (zeta potential of -120 mV). Magnetic hyperthermia and the relaxivities measurements show high efficiency at neutral pH which enables their use for both magnetic hyperthermia and MRI. © 2016 Elsevier B.V. All rights reserved.</style></abstract><notes><style face="normal" font="default" size="100%">cited By 4</style></notes></record></records></xml>