<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dionísio, M.a</style></author><author><style face="normal" font="default" size="100%">Braz, L.b c d</style></author><author><style face="normal" font="default" size="100%">Corvo, M.e</style></author><author><style face="normal" font="default" size="100%">Lourenço, J.P.b f g</style></author><author><style face="normal" font="default" size="100%">Grenha, A.a f</style></author><author><style face="normal" font="default" size="100%">Rosa da Costa, A.M.b f</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Charged pullulan derivatives for the development of nanocarriers by polyelectrolyte complexation</style></title><secondary-title><style face="normal" font="default" size="100%">International Journal of Biological Macromolecules</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Article</style></keyword><keyword><style  face="normal" font="default" size="100%">bovine serum albumin</style></keyword><keyword><style  face="normal" font="default" size="100%">carbohydrate analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">carrageenan</style></keyword><keyword><style  face="normal" font="default" size="100%">chemical modification</style></keyword><keyword><style  face="normal" font="default" size="100%">Chitosan</style></keyword><keyword><style  face="normal" font="default" size="100%">complex formation</style></keyword><keyword><style  face="normal" font="default" size="100%">controlled study</style></keyword><keyword><style  face="normal" font="default" size="100%">cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">hydrogen bond</style></keyword><keyword><style  face="normal" font="default" size="100%">immobilization</style></keyword><keyword><style  face="normal" font="default" size="100%">in vitro study</style></keyword><keyword><style  face="normal" font="default" size="100%">n</style></keyword><keyword><style  face="normal" font="default" size="100%">n dimethylformamide</style></keyword><keyword><style  face="normal" font="default" size="100%">nanocarrier</style></keyword><keyword><style  face="normal" font="default" size="100%">nanoparticle</style></keyword><keyword><style  face="normal" font="default" size="100%">particle size</style></keyword><keyword><style  face="normal" font="default" size="100%">polyelectrolyte</style></keyword><keyword><style  face="normal" font="default" size="100%">polysaccharide</style></keyword><keyword><style  face="normal" font="default" size="100%">pullulan</style></keyword><keyword><style  face="normal" font="default" size="100%">pullulan derivative</style></keyword><keyword><style  face="normal" font="default" size="100%">quaternary ammonium derivative</style></keyword><keyword><style  face="normal" font="default" size="100%">small interfering RNA</style></keyword><keyword><style  face="normal" font="default" size="100%">sorbitan oleate</style></keyword><keyword><style  face="normal" font="default" size="100%">sulfur oxide</style></keyword><keyword><style  face="normal" font="default" size="100%">synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">unclassified drug</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.scopus.com/inward/record.uri?eid=2-s2.0-84956708744&amp;doi=10.1016%2fj.ijbiomac.2016.01.054&amp;partnerID=40&amp;md5=1abfb41140b24550f0c316669c4df223</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">Elsevier</style></publisher><volume><style face="normal" font="default" size="100%">86</style></volume><pages><style face="normal" font="default" size="100%">129-138</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Pullulan, a neutral polysaccharide, was chemically modified in order to obtain two charged derivatives: reaction with SO3.DMF complex afforded a sulfate derivative (SP), while reaction with glycidyltrimethylammonium chloride gave a quaternary ammonium salt (AP). The presence of the charged groups was confirmed by FTIR. Assessment of the positions where the reaction took place was based on 1H- and 13C NMR (COSY, HSQC-TOCSY, HSQC-DEPT, and HMBC) experiments. Estimation of the degree of substitution (DS) was made from elemental analysis data, and further confirmed by NMR peak areas in the case of AP. These new derivatives showed the capability to condense with each other, forming nanoparticles with the ability to associate a model protein (BSA) and displaying adequate size for drug delivery applications, therefore making them good candidates for the production of pullulan-based nanocarriers by polyelectrolyte complexation. © 2016 Elsevier B.V.</style></abstract><notes><style face="normal" font="default" size="100%">cited By 0</style></notes></record></records></xml>